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Updated: Jul 5, 2026

A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation (VCA) Research
Published on: October 14, 2013
[Anatomical basis for vascular-pedicle transplantation of the hypothalamo-hypophyseal complex]
Abstract:
In 240 corpses of mature persons by means of complex morphological methods extraorganic arteries of the hypophysis, anterior hypothalamus have been investigated, as well as topography of the arterial peduncle of the hypothalamo-hypophyseal complex. Blood supply of the hypophysis and of the anterior hypothalamic part is performed from one common vascular pool--the arterial ring of the brain via multiple arterial branches, their amount and diameter varying considerably. Taking into account an important role of anastomotic vessels and numerous arterial plexuses, when the hypothalamo-hypophyseal complex is extirpated for investigation, it is necessary to include into its composition, besides the major arterial peduncle, the optic chiasm, the grey tuber and the system of cavernous sinuses. Owing to this, there is no need to separate the arterial peduncle of the transplant at the moment of obtaining the hypothalamo-hypophyseal complex. The topographic anatomical investigations performed make prerequisites for transplantation of the hypothalamo-hypophyseal complex on the vascular peduncle in clinic.
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