Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

352
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
352
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

576
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
576
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

484
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
484
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

151
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
151
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

451
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
451
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

468
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
468

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The changing landscape of intestinal transplantation: Insights from the first quarter of the 21st century of Eurotransplant experience.

Intestinal Failure (New York, N.Y.)·2026
Same author

Benefit of adjuvant chemotherapy for resected pancreatic cancer following neoadjuvant FOLFIRINOX or Gemcitabine-Nab-paclitaxel: a multinational analysis.

Journal of the National Cancer Institute·2026
Same author

Perioperative outcomes of robotic-assisted liver surgery: A comparison between patients with and without previous abdominal surgery.

Surgery open science·2026
Same author

Conversion to LCP Tacrolimus Mitigates Calcineurin-Induced Nephrotoxicity in Patients After Liver Transplantation.

Clinical transplantation·2026
Same author

[Esophageal NEN: update on diagnostics and surgical treatment].

Chirurgie (Heidelberg, Germany)·2026
Same author

CT-based vascular invasion in pancreatic ductal adenocarcinoma compared with intraoperative and histological findings.

Insights into imaging·2026

Related Experiment Video

Updated: Oct 28, 2025

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

7.3K

[Chronic intestinal failure].

Jens G Brockmann1, Anna Hüsing-Kabar2, Katharina Bohlen2

  • 1Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|July 15, 2021
PubMed
Summary

Intestinal failure (IF) results from lost bowel absorption capacity due to various diseases. Management involves conservative treatment, surgery, or transplantation, with specific small bowel lengths determining potential autonomy.

Keywords:
Bowel transplantationMalabsorptionMultivisceral transplantationNutritional treatmentShort bowel syndrome

More Related Videos

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

9.7K
Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

15.1K

Related Experiment Videos

Last Updated: Oct 28, 2025

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

7.3K
Ileectomy-induced Bile Overaccumulation in Mouse Intestine
06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

9.7K
Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

15.1K

Area of Science:

  • Gastroenterology
  • Abdominal Surgery
  • Transplantation

Background:

  • Intestinal failure (IF) signifies a critical loss of the bowels' absorptive capacity.
  • It encompasses diverse conditions with anatomical or functional origins.
  • Prognosis depends on remaining digestive tract function and small bowel bacterial colonization.

Purpose of the Study:

  • To define intestinal failure (IF).
  • To outline the management spectrum for IF.
  • To establish criteria for potential intestinal autonomy.

Main Methods:

  • Review of existing literature on intestinal failure.
  • Analysis of factors influencing intestinal function and adaptation.
  • Identification of key anatomical and functional parameters for intestinal autonomy.

Main Results:

  • Intestinal failure can be transient or irreversible, stemming from various pathologies.
  • Conservative treatment aims for intestinal adaptation, followed by surgery or transplantation if needed.
  • Specific lengths of the small bowel (e.g., 35-100cm) can support intestinal autonomy depending on colonic and ileocecal valve integrity.

Conclusions:

  • Intestinal failure is a complex condition requiring a tailored management approach.
  • Early intervention and consideration of surgical options or transplantation are crucial.
  • Defining criteria for intestinal autonomy is vital for patient management and outcomes.