A pragmatic evidence-based approach to post-mortem perinatal imaging.

Area of Science:

• Radiology
• Pathology
• Perinatal Medicine

Background:

• Post-mortem imaging is increasingly utilized for perinatal death investigations.
• Existing literature often focuses on specific techniques rather than practical guidance.
• There is a need for evidence-based protocols for real-world application.

Purpose of the Study:

• To review current research on perinatal post-mortem imaging.
• To provide a practical approach and decision-making flowchart for radiologists.
• To guide the selection of appropriate imaging modalities and protocols.

Main Methods:

• Literature review of post-mortem imaging techniques (CT, MRI, ultrasound, micro-CT).
• Analysis of factors influencing diagnostic quality.
• Development of a flowchart for imaging protocol decision-making.
• Inclusion of considerations for image-guided biopsy.

Main Results:

• Summarizes latest research in perinatal post-mortem imaging.
• Highlights crucial maternal and antenatal history elements for protocolling.
• Identifies key factors affecting image quality (e.g., post-mortem interval).

Conclusions:

• Provides a structured approach to perinatal post-mortem imaging referrals.
• Aims to improve the consistency and diagnostic yield of post-mortem imaging.
• Offers essential references for various imaging modalities and protocols.