Related Experiment Video For Noonan syndrome

Updated: Oct 28, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

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The first reported case of Noonan syndrome complicated with hepatocellular carcinoma

Satoru Kakizaki1,2, Daisuke Uehara1, Hiroki Tojima1

  • 1Department of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.

Clinical Case Reports
|July 16, 2021
PubMed

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Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
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Keywords:
Noonan syndromePTPN11hepatocellular carcinoma