Preoperative irradiation in oral cavity carcinoma. A study with special reference to DNA pattern, histological

¹Department of Otolaryngology, University Hospital, Linköping, Sweden.

|January 1, 1987

Abstract:

The relation between DNA pattern and response to preoperative radiotherapy was studied in 51 patients with oral squamous cell carcinomas operated 4 weeks after irradiation. Small tumors (T1 and T2) showed more pronounced response to radiotherapy than larger ones (T3 and T4), as did DNA aneuploid tumors. Eight of 11 DNA aneuploid tumors showed no remaining tumor in the operation specimen, compared to 6 of 21 DNA polyploid and 2 of 19 DNA diploid tumors. None of 16 patients without demonstrable remaining cancer in the operation specimen had local recurrence. The presence of lymph node metastases was the most important prognostic factor.

Related Experiment Videos

Preoperative irradiation in oral cavity carcinoma. A study with special reference to DNA pattern, histological

Related Concept Videos

Co-localization of fibrinolytic activators and inhibitors with macrophages in atherosclerotic vessels.

Nuclear CSPP1 expression defined subtypes of basal-like breast cancer.

Flotillins as regulators of ErbB2 levels in breast cancer.

Flow cytometric measurement of cellular FLICE-inhibitory protein (c-FLIP) in ovarian carcinoma effusions.

Proliferating cell nuclear antigen in adenoid cystic carcinomas of the head and neck.

p53 protein expression in adenoid cystic carcinoma of the head and neck.

Operationalizing fear of cancer recurrence care: a modified Delphi study establishing a consensus-based clinical pathway for Danish cancer survivors.

FIN-EGFR: real-world treatment outcomes by EGFR mutational subtypes in NSCLC in Southern Finland.

Disparities in initiating standard first-line cancer treatment and survival for patients with an immigrant background: a Danish register-based cohort study.

Fatigue 5 years after treatment for rectal cancer – results from the QoLiRECT study

Association between CAR T-cell persistence and improved response to salvage radiotherapy in patients with DLBCL.

Pre-operative circulating tumour DNA in high-risk primary cutaneous melanoma: prospective feasibility in molecular pathology.

Adult-Onset Central Nervous System Erdheim-Chester Disease Successfully Treated With Cladribine and Cytarabine: Case Report and Literature Review.

Management of ectopic Cushing syndrome in medullary thyroid carcinoma: from case reports to systematic literature review.

Treatment switching in oncology evidence synthesis: a systematic review of meta-analytical practices incorporating time-dependent confounding, censoring bias, and patient-level variability.

Association of opioid-based and opioid-free multimodal analgesia with hospital length of stay and postoperative pain in outpatient aesthetic plastic surgery: a retrospective cohort study.

Catatonic Features That May Be Mistaken for Worsening Autism Show Treatment-Associated Improvement: Implications for Later Regression.

Integrative pipeline to profile and target endocrine therapy-insensitive cell populations in ER+ breast cancer.

Related Experiment Videos

Preoperative irradiation in oral cavity carcinoma. A study with special reference to DNA pattern, histological...

Abstract:

Related Concept Videos

Related Articles

Preoperative irradiation in oral cavity carcinoma. A study with special reference to DNA pattern, histological