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Updated: Oct 28, 2025

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
Published on: July 29, 2013
Manufacturing and evaluation of a multi-purpose Iranian head and neck anthropomorphic phantom called MIHAN
Mohammad Ahmadi1, Meysam Ramezani Anarestani2, Sanaz Hariri Tabrizi3
1Department of Medical Radiation Engineering, Shahid Beheshti University, Tehran, Iran.
Abstract:
A new multi-purpose Iranian head and neck (MIHAN) anthropomorphic phantom was designed and manufactured to be used in diagnostic and therapeutic applications. Geometry of MIHAN phantom was determined based on the average dimensions acquired by CT scans of twenty patients without any medical problems in their head and neck site. Because the phantom was expected to be used with different modalities with a wide range of photon energies, attenuation coefficients of some selected materials were determined using Monte Carlo simulation. Based on analytical and simulation results, acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA) were found suitable choices for soft and bony tissues, respectively. They were used in the 3D printer to build the phantom. The suitability of the materials was checked by CT number value comparison between the organs included in the phantom and the corresponding body tissues and also film dosimetry of a typical intensity-modulated radiation therapy (IMRT) plan.. Hounsfield Unit agreement and 95% ± 2% pass rate for the IMRT plan verification proved the suitability of material selection. Also, the film dosimetry showed feasibility of using MIHAN in radiotherapy plan verification workflow. In addition, PLA was introduced as a spongy bone tissue substitute for the first time.

