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Soft Lithographic Functionalization and Patterning Oxide-free Silicon and Germanium
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Facile Surface Functionalization Strategy for Two-Photon Lithography Microstructures.

Junning Zhang1, Haibo Ding1, Xiaojiang Liu1

  • 1State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.

Small (Weinheim an Der Bergstrasse, Germany)
|July 16, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces a versatile surface functionalization method for two-photon lithography (TPL) printed objects. This technique enables diverse functionalities on microstructures without altering their complex 3D designs, expanding TPL applications.

Keywords:
3D printingsurface functionalizationthiol-enetwo-photon lithography

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Surface Chemistry

Background:

  • Two-photon lithography (TPL) enables complex 3D microfabrication but is limited by the chemical functionalities of printed structures.
  • Existing methods for functionalizing TPL-printed objects are often restrictive and material-dependent.
  • There is a need for a broadly applicable and efficient method to impart diverse chemical functionalities onto TPL-fabricated microstructures.

Purpose of the Study:

  • To develop a facile, efficient, and widely applicable method for surface functionalization of TPL-printed objects.
  • To demonstrate the introduction of various chemical functionalities without compromising micro-nano topographies.
  • To showcase the utility of this method for creating functional microstructures and its application in biofunctionalization.

Main Methods:

  • Surface treatment of TPL-printed objects using trichlorovinylsilane.
  • Subsequent functionalization via thiol-ene click chemistry.
  • Application of the method to diverse materials including metals, metal oxides, and plastics.

Main Results:

  • Successful and efficient surface functionalization of TPL-printed objects regardless of their base composition.
  • Introduction of various functionalities without altering the intricate micro-nano surface topographies.
  • Demonstrated biofunctionalization of microrobots and cell scaffolds, highlighting practical applications.

Conclusions:

  • The developed method provides a fast, highly efficient, and photoresist-independent approach for functionalizing TPL microstructures.
  • This technique significantly broadens the scope of TPL applications by enabling the creation of diverse functional micro-devices.
  • The method's versatility across different materials and its successful biofunctionalization applications underscore its potential impact in microfabrication and biomedical engineering.