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Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
A method for fundus evaluation in children with oral fluorescein
1Paediatric Ophthalmology Service, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All-India Institute of Medical Sciences, New Delhi.
The British Journal of Ophthalmology
|December 1, 1987
Summary
Oral fluorescein ingestion allows safe ophthalmoscopic fundus examination in children without sedation. This technique visualizes retinal fluorescence, offering a new diagnostic approach for pediatric eye conditions.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Medical Imaging
Background:
- Ophthalmoscopic examination of the pediatric fundus often requires sedation or anesthesia.
- Non-invasive imaging techniques are crucial for evaluating pediatric eye health.
Purpose of the Study:
- To describe a novel procedure for ophthalmoscopic fundus examination in children.
- To evaluate the safety and efficacy of oral fluorescein for pediatric fundus visualization.
Main Methods:
- Administration of 1% or 2% oral fluorescein to healthy children.
- Ophthalmoscopic examination of the fundus at 15, 30, and 60 minutes post-ingestion.
- Absence of sedation or anesthesia during the procedure.
Main Results:
- The procedure was performed without major complications or allergic reactions.
- Fluorescence of the nerve head and retinal blood vessels was visualized.
- Fluorescence peaked at 30 minutes and declined by 60 minutes.
Conclusions:
- Oral fluorescein ingestion is a safe and effective method for ophthalmoscopic fundus examination in children.
- This technique provides a viable alternative to sedation-based examinations.
- Further research into potential complications and applications is warranted.
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