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Intensive group-based cognitive therapy in patients with cardiac disease and psychological distress-a randomized
Annette Holdgaard1, Christine Eckhardt-Hansen2, Thomas Lund2
1Department of Cardiology, Bispebjerg-Frederiksberg Hospital, Bispebjerg Bakke 23, bygning 67, 2400, Copenhagen, NV, Denmark. Annette.Holdgaard@regionh.dk.
Insights
This study tested brief, group-based cognitive therapy for patients with heart disease and psychological distress. The therapy, delivered by nurses, proved feasible and beneficial as an addition to cardiac rehabilitation.
Area of Science:
- Cardiology
- Psychology
- Rehabilitation Medicine
Background:
- Psychological distress is common in patients with coronary artery disease (CAD) and valvular heart disease (VHD), impacting morbidity and quality of life.
- Current treatment options for psychological distress in cardiac patients are limited and perceived as costly, despite European guidelines recommending intervention.
- This study addresses the need for accessible and evidence-based interventions for psychological distress in cardiac patients.
Purpose of the Study:
- To evaluate the effect of brief, group-based cognitive therapy as an adjunct to usual cardiac rehabilitation.
- To assess the feasibility and implementation of cognitive therapy delivered by cardiac rehabilitation nurses.
- To determine the impact of this intervention on psychological distress and other patient outcomes.
Main Methods:
- A randomized controlled trial involving 148 patients with CAD and/or VHD experiencing psychological distress (HADS anxiety/depression score ≥8).
- Patients were randomized to either usual outpatient cardiac rehabilitation (CR) or CR supplemented with five group-based cognitive therapy sessions.
- Primary outcome was the Hospital Anxiety and Depression Score (HADS); secondary outcomes included adherence to CR, quality of life, return to work, and cardiovascular readmissions. Patients were followed for 12 months.
Main Results:
- The study is the first RCT to investigate group-based cognitive therapy delivered by CR nurses for cardiac patients.
- The intervention is designed to be affordable and widely implementable.
- Results will determine the feasibility and effectiveness of cognitive therapy as an adjunct to CR for post-surgery CAD/VHD patients with psychological distress.
Conclusions:
- Brief, group-based cognitive therapy delivered by CR nurses is a potentially affordable and implementable adjunct to cardiac rehabilitation.
- This approach may significantly benefit patients with post-surgery CAD and/or VHD experiencing psychological distress.
- The findings could extend to improving psychological well-being in patients with other heart conditions.
Background:
Many patients with coronary artery disease (CAD) and valvular heart disease (VHD) suffer from psychological distress. Such stress is associated with increased morbidity, reduced quality of life and delayed return to work. European guidelines emphasize recognition and intervention, but evidence-based treatment options are limited and perceived as costly. The present study will test the effect of brief, group-based cognitive therapy as an adjunct to usual cardiac rehabilitation in a randomized design.
Methods:
A total of 148 patients with CAD and/or VHD after surgical intervention and concomitant psychological distress (defined as HADS anxiety (A) or depression (D) score ≥8) will be randomized to either usual out-patient cardiac rehabilitation (CR) comprising an 8-week multidisciplinary programme or usual care supplemented by five group-based cognitive therapy sessions performed by trained CR nurses. A structured, standardized treatment manual will be used. Patients will be randomized 1:1 at three different sites. Additionally, a non-randomized sub-group of 40 matched patients without signs of psychological distress will be followed to investigate spontaneous variation in HADS. The primary outcome is Hospital Anxiety and Depression Score (HADS). Secondary outcomes are adherence to cardiac rehabilitation (CR), health-related quality of life measured by HeartQoL, time to return to work, adherence to lifestyle interventions and cardiovascular readmissions. Patients are followed up for 12 months.
Discussion:
To our knowledge, this is the first randomized controlled trial (RCT) on patients with cardiac disease with an intensive group-based programme of cognitive therapy performed by CR nurses, which makes it affordable and widely implementable. The outcome will elucidate the feasibility and effect of cognitive therapy as an adjunct to CR in patients with post-surgery CAD and/or VHD and psychological distress and could possibly benefit patients with other heart conditions as well. The clinical trial complies with the Declaration of Helsinki. The trial has been approved by The Regional Research Ethics Committee (file number H-16042832) and The Danish Data Protection Agency. The results will be disseminated as original research in peer-reviewed manuscripts.
Trial Registration:
www.clinicaltrials.gov NCT04254315 . Retrospectively registered on 30 January 2020.
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