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Case Study 5: Predicting the Drug Interaction Potential for Inhibition of CYP2C8 by Montelukast

Ken Korzekwa1

  • 1Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USA. korzekwa@temple.edu.

Methods in Molecular Biology (Clifton, N.J.)
|July 17, 2021
PubMed

Keywords:
CYP2C8Cheng-Prusoff equationDrug-drug interactionFraction unboundFree drug hypothesisMicrosomal proteinsMontelukastProtein binding

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