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Aortic stenosis and right ventricular dysfunction

Pavol Fülöp, Marianna Dvorožňáková, Gabriel Valočik

    Vnitrni Lekarstvi
    |July 19, 2021
    PubMed

    Insights

    Severe aortic stenosis (AS) causes systemic cardiac damage, including right ventricular dysfunction. Assessing right ventricular function is crucial for identifying patients who may benefit most from intervention.

    Area of Science:

    • Cardiology
    • Cardiac Physiology

    Background:

    • Severe aortic stenosis (AS) involves systemic cardiac damage beyond the aortic valve and left ventricle.
    • Right ventricular dysfunction is common in AS patients due to ventricular interdependence.

    Purpose of the Study:

    • To propose a new classification of AS based on myocardial damage.
    • To highlight the prognostic significance of right ventricular dysfunction in severe AS.
    • To advocate for standardized echocardiographic assessment of right ventricular function in severe AS.

    Main Methods:

    • Review of existing literature on cardiac damage in severe AS.
    • Analysis of echocardiographic data focusing on right ventricular function.
    • Correlation of right ventricular dysfunction with mortality rates.

    Main Results:

    • Severe AS is a systemic disease with significant cardiac structural and functional alterations.
    • Right ventricular dysfunction is prevalent and linked to increased mortality in severe AS patients.
    • Patients with right ventricular dysfunction may experience greater benefits from intervention.

    Conclusions:

    • A new classification for AS based on myocardial damage is proposed.
    • Right ventricular dysfunction is a critical factor in the prognosis of severe AS.
    • Standardized echocardiographic evaluation of right ventricular function is essential for managing severe AS patients.

    Keywords:
    TAVIaortic stenosisright ventricular dysfunction

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