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Meningiomas in childhood
V R Kolluri1, D R Reddy, P K Reddy
1Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.
Insights
Pediatric meningiomas are reviewed, showing a 1:1 sex ratio and a tendency for supratentorial location and large size. Some cases exhibited sarcomatous changes or cystic features.
Area of Science:
- Neuro-oncology
- Pediatric Neurosurgery
- Pathology
Background:
- Meningiomas are typically adult tumors.
- Pediatric meningiomas are rare and less understood.
- Understanding their characteristics is crucial for diagnosis and treatment.
Purpose of the Study:
- To review the clinical and pathological features of pediatric meningiomas.
- To identify common presentations and characteristics in children.
- To contribute to the knowledge base of rare pediatric tumors.
Main Methods:
- Retrospective review of 18 pediatric meningioma cases.
- Histological verification of all tumors.
- Analysis of clinical presentation, tumor location, size, and pathological findings.
Main Results:
- A 1:1 sex ratio was observed.
- Two patients presented with seizures.
- Most tumors were supratentorial and large.
- Sarcomatous changes were noted in 4 cases.
- Cystic features were present in 6 cases.
Conclusions:
- Pediatric meningiomas present unique characteristics compared to adult counterparts.
- Supratentorial location and large size are common.
- The presence of sarcomatous or cystic changes warrants further investigation.
Abstract:
The clinical presentation and pathological characteristics of 18 histologically verified meningiomas in the paediatric age group are reviewed. There was a 1:1 sex ratio. Two children presented with seizures. The majority were supratentorial in location and large in size. In 4 patients, the meningiomas showed sarcomatous changes, while in 6 patients they were cystic.