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Author Spotlight: Exploring Strategies for Successful Immune Response Against Tumors
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Research progress of omics technology in the field of tumor resistance: From single-omics to multi-omics combination

Ze'en Sun1,2, Yujie Liu3,4, Qianying Ouyang3,4

  • 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008. 198111138@csu.edu.cn.

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences
|July 19, 2021
PubMed

Insights

Drug resistance poses a major challenge in cancer therapy. Multi-omics approaches are accelerating the discovery of new therapeutic targets to overcome this resistance.

Area of Science:

  • Oncology and Molecular Biology
  • Genomics and Bioinformatics

Background:

  • Drug resistance is a primary obstacle in effective cancer treatment.
  • Identifying novel therapeutic targets is crucial for overcoming treatment failure.

Purpose of the Study:

  • To highlight the significance of studying cancer drug resistance mechanisms.
  • To emphasize the role of multi-omics in accelerating the discovery of new therapeutic targets.

Main Methods:

  • Utilizing multi-omics data, including genomics, epigenomics, transcriptomics, proteomics, metabolomics, and radiomics.
  • Analyzing complex biological datasets to understand tumor resistance.

Main Results:

  • Multi-omics research has significantly advanced the understanding of tumor resistance.
  • This accelerated discovery of novel therapeutic targets for cancer treatment.

Conclusions:

  • Multi-omics strategies are vital for deciphering cancer drug resistance.
  • Continued research in this area promises to yield new clinical strategies to combat cancer.
Keywords:
epigenomicsgenomicsmetabolomicsproteomicsradiomicstranscriptomicstumor resistance

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