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Cardiovascular Manifestations and Outcomes in Patients Admitted with Severe COVID-19: Middle Eastern Country

Fahad Alkindi1, Khamis Alhashmi2, Sunil Nadar1

  • 1Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.

Heart Views : the Official Journal of the Gulf Heart Association
|July 19, 2021
PubMed

Insights

Severe COVID-19 patients admitted to the ICU frequently experienced cardiovascular issues, primarily myocardial injury. This cardiac involvement significantly increased the risk of mortality in these critically ill patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Severe COVID-19, caused by SARS-CoV-2, can impact the cardiovascular system.
  • Understanding cardiovascular manifestations in severe cases is crucial for patient outcomes.

Purpose of the Study:

  • To assess cardiovascular manifestations in severe COVID-19 patients.
  • To determine the effect of these manifestations on mortality in ICU patients.

Main Methods:

  • Retrospective, multicenter cohort study.
  • Included adult patients with laboratory-confirmed COVID-19 admitted to ICUs in Oman.
  • Data collected between March 1, 2020, and August 10, 2020.

Main Results:

  • 541 patients were included; 16.5% died during hospitalization.
  • 34.2% showed evidence of cardiac involvement, including raised troponin (31.6%).
  • Cardiovascular involvement, particularly high troponin, was strongly associated with increased mortality (OR=8.8).

Conclusions:

  • A significant proportion of severe COVID-19 patients exhibit cardiovascular involvement, mainly myocardial injury.
  • Cardiovascular complications are linked to a higher risk of death in critically ill COVID-19 patients.
Abstract

Keywords:
COVID-19Cardiovascular manifestationsSARS-CoV-2mortalitytroponin

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