Radiation-Induced Pan-Valvular Involvement: A Rare Case Report.

Area of Science:

• Cardiology
• Oncology
• Radiology

Background:

• Radiotherapy is a crucial treatment for thoracic malignancies.
• Long-term complications include radiation-associated valve disease (RAVD).

Observation:

• A patient with a history of radiotherapy for breast cancer, 30 years prior.
• Presented with clinically significant RAVD.

Findings:

• The patient exhibited RAVD involving all four cardiac valves.
• Simultaneous, multi-valve involvement in RAVD is exceptionally rare.

Implications:

• Highlights the potential for delayed, severe cardiac complications following radiotherapy.
• Emphasizes the need for long-term cardiovascular surveillance in radiation-treated patients.
• Suggests further research into the mechanisms and management of extensive RAVD.