Related Experiment Video
Updated: Oct 28, 2025

A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy
Published on: November 7, 2017
The need for a cardionephrology subspecialty
Javier Díez1,2, Alberto Ortiz3,4
1Departments of Nephrology and Cardiology, University of Navarra Clinic, Pamplona, Spain.
Insights
Chronic kidney disease (CKD) significantly impacts cardiovascular health, leading to frequent complications and unmet medical needs. Enhanced nephrologist training in cardionephrology is crucial for managing these intertwined conditions effectively.
Area of Science:
- Nephrology and Cardiology
- Cardiorenal Medicine
Background:
- Chronic kidney disease (CKD) presents significant structural and functional cardiovascular repercussions, increasing the risk of cardiovascular disease (CVD).
- Cardiovascular complications are highly prevalent in CKD patients, imposing a substantial clinical, public health, and economic burden.
- The management of cardiovascular complications in CKD remains an unmet medical need, partly due to insufficient cardiovascular training among nephrologists.
Discussion:
- A paradigm shift is required to recognize CKD as a condition where cardiovascular manifestations necessitate dedicated, multidisciplinary clinical management.
- Cardionephrology training for nephrologists is proposed as a solution to provide adequate cardiovascular care for CKD patients.
- Cardionephrology subspecialists can facilitate better interaction within multidisciplinary teams for improved understanding and management of CKD-CVD interactions.
Key Insights:
- CKD profoundly affects the cardiovascular system, making CVD a leading cause of morbidity and mortality in this population.
- There is a critical need for improved cardiovascular education within nephrology training programs.
- Multidisciplinary care, spearheaded by cardionephrology expertise, is essential for addressing the complex interplay between CKD and CVD.
Outlook:
- Integrating cardionephrology into nephrology specialization will enhance the capacity of nephrologists to manage cardiovascular risks in CKD.
- Establishing dedicated multidisciplinary clinics focused on cardionephrology will improve patient outcomes and reduce healthcare costs.
- Further research into the specific mechanisms linking CKD and CVD will inform more targeted therapeutic strategies.
Abstract:
Chronic kidney disease (CKD) has structural and functional repercussions for the cardiovascular system that facilitate the development of cardiovascular disease (CVD). In fact, cardiovascular complications are frequent in the CKD population and thus cause a great clinical, public health and economic burden. Despite this challenge, the prevention and management of cardiovascular complications is one among several aspects of CKD that meets the criteria of an unmet medical need. This probably has to do with the misperception by the nephrologist of the global relevance of CVD in the CKD patient which, in turn, may be due to insufficient cardiovascular training during nephrology specialization. Therefore a change in approach is necessary to understand CKD as a disease in which the manifestations and complications related to CVD become so frequent and important that they require dedicated multidisciplinary clinical management. From this perspective, it makes sense to consider training in the subspecialty of cardionephrology to provide adequate cardiovascular care for CKD patients by the nephrologist. In addition, the cardionephrology subspecialist would be better able to interact with other specialists in multidisciplinary care settings created to achieve a deeper understanding and more effective clinical handling of the interactions between CKD and CVD.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Cardiomyopathy V: Interprofessional Care
Chronic Kidney Disease IV: Nursing Management
Cardiac Catheterization I: Pre-Procedure Overview
Cardiomyopathy II: Dilated Cardiomyopathy
Nephrons

