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Updated: Oct 28, 2025
A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Sickle Cell Disease and the Respiratory System: A Tangential Perspective to the Hematopulmonological Dilemma
Ibrahim Sange1,2, Phani Bhavana Cherukuri3, Vaishnavi Parchuri4
1Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Abstract:
Sickle cell disease (SCD) is a genetically inherited hematological condition that predominantly affects the African-American subset of the population. It leads to the precipitation of multi-systematic manifestations throughout the course of the life of the patient leading to an increased rate of inpatient admissions and decreased quality of life. This article has reviewed some of the most common pulmonary complications of SCD with a brief overview of the clinical features and their management and has also highlighted the fatality of the complications placing a strong focus on screening, monitoring, and the treatment of the disease. The article has also discussed the management of SCD from a pulmonological perspective rather than hematological alone.
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