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Diffuse Large B-Cell Lymphoma of the Left Upper Extremity Mimicking a Sarcoma
Raheel S Siddiqui1, Debra Ferman2, Sandeep Tuli3
1Department of Internal Medicine, Icahn School of Medicine at Mount Sinai, New York City Health and Hospitals/Queens, Jamaica, USA.
Cureus
|July 19, 2021
Summary
Diffuse large B-cell lymphoma (DLBCL) rarely presents as a soft tissue mass in the upper extremity. This case highlights the importance of considering lymphoma in differential diagnoses to prevent misdiagnosis and unnecessary surgical interventions.
Area of Science:
- Oncology
- Pathology
Background:
- Diffuse large B-cell lymphoma (DLBCL) commonly affects lymph nodes but can occur in extranodal sites.
- Soft tissue masses in the upper extremity are often presumed to be sarcomas.
Observation:
- A 64-year-old woman presented with a large left upper arm mass.
- The mass was surgically resected under the initial diagnosis of sarcoma.
Findings:
- Final pathology revealed the mass to be DLBCL, not sarcoma.
- This case demonstrates an unusual presentation of DLBCL in the soft tissue of the upper extremity.
Implications:
- Accurate diagnosis is crucial to avoid inappropriate treatments like extensive surgery for lymphoma.
- Clinicians should consider extranodal lymphomas in the differential diagnosis of soft tissue masses.
- Early recognition of lymphoma can lead to timely and appropriate oncologic management.
