Related Experiment Video
Updated: Oct 28, 2025

08:14
An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
Published on: October 6, 2015
10.4K
Psychiatric Comorbidities in Pediatric Inpatients With Human Immunodeficiency Virus Infection and Impact on Hospital
Caroline C Dias1, Victoria Ayala2, Fartun A Aliduux3
1Psychiatry, Yenepoya Medical College and Hospital, Mangalore, IND.
Cureus
|July 19, 2021
Summary
Pediatric inpatients with human immunodeficiency virus (HIV) infection have higher risks of depression and psychosis. These children also experience longer hospital stays, increasing healthcare costs.
Area of Science:
- Pediatric Health
- Infectious Diseases
- Mental Health
Background:
- Pediatric psychiatric comorbidities are a significant concern.
- Human immunodeficiency virus (HIV) infection can impact mental health in children.
- Understanding these associations is crucial for effective healthcare management.
Purpose of the Study:
- To identify psychiatric comorbidities in pediatric inpatients with and without HIV.
- To assess the impact of HIV on the length of hospital stay (LOS) and treatment costs.
- To compare the prevalence of specific psychiatric conditions between HIV-positive and HIV-negative pediatric patients.
Main Methods:
- A case-control study utilizing the Nationwide Inpatient Sample.
- Inclusion of 4,920 pediatric inpatients aged 6-18, matched for demographics.
- Logistic regression and independent sample t-tests to analyze psychiatric comorbidities, LOS, and costs.
Main Results:
- HIV-positive children showed higher rates of anxiety (6.9%), drug abuse (6.6%), psychosis (6.4%), and depression (6.2%).
- Significantly increased odds of psychosis (aOR: 1.82) and depression (aOR: 1.79) were observed in HIV-positive patients.
- Mean LOS was longer for HIV-positive inpatients (11.1 days vs. 6.0 days).
Conclusions:
- HIV-positive pediatric patients face a substantially higher risk of depression and psychosis.
- Hospitalization for HIV-positive children is prolonged, contributing to increased healthcare expenditures.
- This highlights the need for integrated mental health support in pediatric HIV care.
Related Concept Videos
Pulmonary Tuberculosis I
427
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
427
Immunodeficiency Diseases
1.3K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
1.3K
Sexually Transmitted Infections
502
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
502
Pharmacokinetics in Pediatric Patients: Drug Excretion
47
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
47
Factors Affecting the Risk of Infection
12.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.8K
Retrovirus Life Cycles
47.8K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
47.8K

