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A Rare Case of Small Bowel Extramedullary Plasmacytomas Presenting With Intestinal Obstruction
Lynna Alnimer1, Ali Zakaria2, Bayan Alshare3
1Department of Internal Medicine, Ascension Providence Hospital-Michigan State University/College of Human Medicine, Southfield, USA.
Cureus
|July 19, 2021
Summary
Extramedullary plasmacytoma (EMP) is a rare plasma cell tumor affecting soft tissues. This case highlights multiple small bowel plasmacytomas causing obstruction, requiring surgical resection and chemotherapy.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm distinct from multiple myeloma, lacking bone marrow involvement or bone lesions.
- Gastrointestinal (GI) involvement, particularly in the small intestine, can manifest with diverse symptoms like bleeding, obstruction, and pain.
- Diagnosis of EMP can be challenging due to its indolent nature and infrequent occurrence.
Observation:
- A 51-year-old female presented with symptoms of small bowel obstruction.
- Diagnostic workup confirmed multiple small bowel plasmacytomas.
Findings:
- The patient underwent surgical resection for the small bowel obstruction.
- Histopathological confirmation of extramedullary plasmacytoma in the small intestine was obtained.
Implications:
- This case underscores the diagnostic challenges and varied presentations of small bowel EMP.
- Prompt diagnosis and multidisciplinary management, including surgery and chemotherapy, are crucial for patient outcomes.
- Further research into optimal treatment strategies and long-term surveillance for GI EMP is warranted.
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