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Updated: Oct 27, 2025

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Two Urgency Categories, Same Outcome: No Difference After "Therapeutic" vs. "Prophylactic" Fasciotomy
Benjamin J Moran1, Megan T Quintana2, Thomas Michael Scalea3
1Department of General Surgery, Albert Einstein Medical Center, Philadelphia, PA, USA.
Fasciotomy is frequently performed with femoropopliteal artery injury repair. Both therapeutic and prophylactic fasciotomies yield similar outcomes, though primary closure is faster than skin grafting.
Area of Science:
- Vascular surgery
- Trauma management
- Compartment syndrome treatment
Background:
- Fasciotomy is a critical intervention for managing compartment syndromes in patients with arterial injuries.
- Below-knee fasciotomy is often considered in conjunction with femoropopliteal arterial injury repair.
Purpose of the Study:
- To document the incidence, indications, and outcomes of below-knee fasciotomy in patients with femoropopliteal arterial injuries.
- To compare outcomes between therapeutic and prophylactic fasciotomies and evaluate closure techniques.
Main Methods:
- Utilized the PROspective Observational Vascular Injury Treatment (PROOVIT) registry.
- Identified patients undergoing two-incision, four-compartment fasciotomy post-femoropopliteal arterial repair.
- Compared outcomes based on fasciotomy indication (therapeutic vs. prophylactic) and closure method (primary vs. split-thickness skin graft).
Main Results:
- Fasciotomy was performed in 158 patients, with 95.6% done at the initial operation.
- Among survivors, 58.3% had therapeutic fasciotomy and 41.7% had prophylactic fasciotomy.
- No significant difference in amputation rates between therapeutic and prophylactic groups; primary closure was faster than split-thickness skin grafting (STSG).
Conclusions:
- Over 55% of patients with femoral or popliteal artery injuries undergo concurrent fasciotomy.
- Therapeutic fasciotomy remains more common than prophylactic, but both demonstrate equivalent outcomes.
- Primary skin closure is a more efficient method compared to STSG for fasciotomy wounds.
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