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Intranuclear distribution of the non-histone proteins: evidence for their compartmentalization
N Yancheva1, E Ivanova, L Djondjurov
1Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Abstract:
1. Qualitative and quantitative distribution of the non-histone proteins in nuclear matrix, chromatin, a new type of RNP-network and nucleosol of Friend cells have been investigated. 2. The specific territorial distribution and metabolism of these proteins found support for the idea of their exact compartmentalization. 3. Since the majority of the non-histone proteins belong to the protein moiety of nuclear RNP-structures their specific territorial distribution probably express a primary compartmentalization of the nuclear ribonucleoproteins.