Related Experiment Video

Updated: Oct 27, 2025

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

3.0K

Progression in Moyamoya Disease: Clinical Features, Neuroimaging Evaluation, and Treatment

Xin Zhang1,2,3,4,5, Weiping Xiao1,2,3,4,5, Qing Zhang6

  • 1Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Current Neuropharmacology
|July 19, 2021
PubMed

Insights

Moyamoya disease (MMD) is a rare cerebrovascular condition causing artery narrowing. This review covers MMD

Area of Science:

  • Neurology
  • Vascular Biology
  • Medical Imaging

Background:

  • Moyamoya disease (MMD) is a chronic cerebrovascular disorder.
  • It involves progressive stenosis of the circle of Willis arteries and collateral vessel formation.
  • MMD presents with complex clinical manifestations, necessitating comprehensive understanding.

Purpose of the Study:

  • To review recent advancements in understanding Moyamoya disease.
  • To discuss updated clinical features, neuroimaging evaluations, and treatment strategies for MMD.
  • To provide a consolidated overview of MMD research progress.

Main Methods:

  • Literature review of recent studies on Moyamoya disease.
  • Analysis of epidemiological, genetic, and pathophysiological data.
  • Evaluation of neuroimaging techniques and therapeutic interventions.

Main Results:

  • Neuroimaging techniques have significantly enhanced the understanding of MMD's structural and functional aspects.
  • Current treatments focus on neurological protection, revascularization, and rehabilitation.
  • Progress has been made in clarifying MMD's clinical features and pathophysiology.

Conclusions:

  • Continued research is vital for improving MMD diagnosis and management.
  • Multidisciplinary approaches combining imaging and therapeutic interventions are key.
  • Further understanding of MMD pathophysiology may lead to novel treatment strategies.
Keywords:
EpidemiologyMoyamoya diseasegenetic characteristicsneuroimagingpathogenesisprogressiontreatment

More Related Videos

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

2.4K
Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases07:47

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Published on: December 6, 2016

7.3K

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
55
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
53
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
113
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
882
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
92
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
97