[Spinal deformity in Duchenne muscular dystrophy]

Area of Science:

• Pediatric Orthopedics
• Neuromuscular Disorders
• Spinal Surgery

Background:

• Duchenne muscular dystrophy (DMD) affects boys, leading to progressive muscle weakness.
• Scoliosis affects 95% of boys with DMD, significantly impacting quality of life.
• Conservative scoliosis management in DMD is largely ineffective.

Purpose of the Study:

• To review the management of scoliosis in Duchenne muscular dystrophy.
• To highlight the role of corticosteroids and surgical interventions.
• To emphasize the importance of an interdisciplinary approach.

Main Methods:

• Review of current literature on scoliosis management in DMD.
• Analysis of treatment outcomes for corticosteroids and surgical spine fusion.
• Discussion of modern surgical techniques and their impact on patient function.

Main Results:

• Corticosteroid treatment may prevent scoliosis in some DMD patients.
• Early surgical intervention (spine fusion) is recommended before significant cardiopulmonary decline.
• Modern surgical techniques allow for preservation of sitting ability and quality of life.
• A moderate complication rate is associated with current surgical approaches.

Conclusions:

• Scoliosis is a near-universal complication of Duchenne muscular dystrophy.
• Timely surgical intervention is crucial for managing scoliosis in DMD.
• An interdisciplinary team approach is essential for optimizing outcomes in DMD patients with scoliosis.