[Spinal deformity in Duchenne muscular dystrophy]
Related Experiment Video
Updated: Oct 27, 2025

Assessing Functional Performance in the Mdx Mouse Model
Published on: March 27, 2014
Ralf Stücker1,2, Sebastian Stücker3,4, Kiril Mladenov3,4
1Kinderorthopädische Abteilung, Altonaer Kinderkrankenhaus, Bleickenallee 38, 22763, Hamburg, Deutschland. ralf.stuecker@kinderkrankenhaus.net.
Abstract:
Boys with Duchenne muscular dystrophy develop scoliosis in 95% of cases. Conservative management to avoid progression of the deformity is not successful. However, treatment with corticosteroids may avoid the onset of scoliosis in some patients. Early surgical treatment and spine fusion is usually recommended before severe cardiopulmonary symptoms have developed. With modern surgical techniques, the sitting ability and quality of life can be preserved with a moderate complication rate. An interdisciplinary approach is mandatory to achieve these goals.
More Related Videos
09:18Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
10:30Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
Published on: May 24, 2016
Related Concept Videos
Satellite Stem Cells and Muscular Dystrophy
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Sex-linked Disorders
Vertebral Column: Regions and Curvature
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
Deformations in a Symmetric Member in Bending
When the member is segmented into tiny cubic elements, it is observed that the primary stress...