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Published on: March 15, 2022
[Anticoagulation and platelet aggregation inhibition : What needs to be considered in the ophthalmological practice]
Oliver Zeitz1, Laura Wernecke2, Nicolas Feltgen3
1Campus Benjamin Franklin, Augenklinik, Charité Universitätsmedizin Berlin, Hindenburgdamm 30, 12202, Berlin, Deutschland. oliver.zeitz@charite.de.
Insights
Elderly patients often need eye surgery and may be on anticoagulation therapy. This review covers pharmacological hemostasis options and their management during ophthalmic procedures.
Area of Science:
- Ophthalmology
- Internal Medicine
- Pharmacology
Background:
- Eye diseases requiring surgery are common in the elderly.
- Many elderly patients have systemic comorbidities requiring anticoagulation.
- Managing anticoagulation in patients undergoing eye surgery is complex.
Purpose of the Study:
- To provide an overview of pharmacological hemostasis options.
- To discuss the importance of anticoagulation management in internal medicine for ophthalmic surgery.
- To analyze literature on interrupting or altering anticoagulation for eye surgery.
Main Methods:
- Literature review of pharmacological hemostasis.
- Analysis of anticoagulation adjustment strategies.
- Discussion of drug options for influencing hemostasis.
Main Results:
- The number of anticoagulation options has increased with new drugs.
- Understanding hemostasis management is crucial for internal medicine.
- Literature analysis informs decisions on anticoagulation modification for eye surgery.
Conclusions:
- Pharmacological hemostasis management is essential for elderly patients undergoing eye surgery.
- Newer anticoagulation drugs require careful consideration.
- Evidence-based strategies are needed for safe perioperative anticoagulation management.
Abstract:
Several eye diseases requiring surgical intervention occur predominantly in elderly. Therefore, there is a significant co-incidence with systemic co-morbidities, which often do require anti-coagulation. There are several approaches to influence hemostasis pharmacologically. The number of options has increased substantially due to introduction of new drugs. This article provides an overview on the option range and gives insight, why this is of importance from the perspective of internal medicine. In addition, the basic principles of adjusting the therapy is being reviewed. Furthermore, the pharmacological inhibition of hemostasis in the context of eye surgery is being discussed. Available literature is analyzed to understand the necessity to interrupt or change the anti-coagulation for eye surgery.
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