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Updated: Oct 27, 2025

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
The role of Doppler ultrasonography in vascular access surveillance-controversies continue
Jan Malik1,2, Carlo Lomonte3, Mario Meola4
1Center for Vascular Access, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Insights
Duplex Doppler ultrasound surveillance for arteriovenous access stenosis in hemodialysis patients shows conflicting results. Standardized criteria are needed to improve diagnosis and prolong access patency.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Chronic hemodialysis necessitates reliable vascular access, with arteriovenous fistulas and grafts preferred over catheters due to lower morbidity and mortality.
- Stenosis in these accesses reduces blood flow, leading to inadequate dialysis and potential thrombosis.
- Current guidelines do not universally recommend ultrasound surveillance for asymptomatic stenosis.
Purpose of the Study:
- To review existing trials on duplex Doppler ultrasound surveillance for arteriovenous access stenosis.
- To analyze the reasons behind conflicting trial results and guideline recommendations.
- To highlight the need for standardized criteria for diagnosing significant stenosis.
Main Methods:
- Systematic review of published trials investigating duplex Doppler ultrasound for arteriovenous access stenosis.
- Analysis of study methodologies, outcome measures, and reported results.
- Evaluation of existing meta-analyses and their limitations.
Main Results:
- Conflicting evidence exists regarding the efficacy of ultrasound surveillance in prolonging access patency.
- Lack of standardized criteria for defining significant stenosis complicates interpretation of trial data.
- Meta-analyses performed on existing studies are limited by methodological heterogeneity.
Conclusions:
- Standardized, precise criteria for identifying significant arteriovenous access stenosis are crucial for accurate diagnosis.
- Further research with standardized protocols is needed to clarify the role of ultrasound surveillance in hemodialysis access management.
- Improved diagnostic criteria may lead to more effective interventions and better patient outcomes.
Abstract:
Chronic hemodialysis therapy required regular entry into the patient's blood stream with adequate flow. The use of arteriovenous fistulas and grafts is linked with lower morbidity and mortality than the use of catheters. However, these types of accesses are frequently affected by stenoses, which decrease the flow and lead to both inadequate dialysis and access thrombosis. The idea of duplex Doppler ultrasound surveillance is based on the presumption that in-time diagnosis of an asymptomatic significant stenosis and its treatment prolongs access patency. Details of performed trials are conflicting, and current guidelines do not support ultrasound surveillance. This review article summarizes the trials performed and focuses on the reasons of conflicting results. We stress the need of precise standardized criteria of significant access stenosis and the weakness of the metaanalyses performed.
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