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Related Experiment Videos

Drug utilization study methodologies: national and international perspectives.

J Serradell1, D C Bjornson, A G Hartzema

  • 1Department of Social and Administrative Pharmacy, College of Pharmacy, University of Minnesota, Minneapolis.

Drug Intelligence & Clinical Pharmacy
|December 1, 1987
PubMed
Summary

This study reviews drug utilization activities, methodologies, and databases in pharmacoepidemiology. It compares North American and European methods for measuring drug consumption, highlighting drug utilization

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Area of Science:

  • Pharmacoepidemiology
  • Drug Utilization Research

Background:

  • Drug utilization activities are crucial in pharmacoepidemiology.
  • Understanding these activities requires robust methodologies and data.
  • The series aims to detail the evolution and current state of drug utilization.

Purpose of the Study:

  • To describe the history, development, and current status of drug utilization activities.
  • To evaluate methodologies used in drug utilization studies.
  • To compare different approaches for measuring drug consumption rates.

Main Methods:

  • Review of historical development and present status of drug utilization activities.
  • Evaluation of various methodologies employed in drug utilization studies.
  • Analysis of principal drug databases for utilization research.

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  • Comparative analysis of North American (patient usage/drug cost) and European (defined daily dose) methods.

    • Main Results:

    • Drug utilization activities have a significant history and evolving methodologies.
    • Key drug databases are available for research.
    • Comparison reveals differences in validity between North American and European measurement approaches.
    • Drug utilization provides essential denominator data for pharmacoepidemiological research.

    Conclusions:

    • Drug utilization research is fundamental to pharmacoepidemiology.
    • Methodological rigor in drug utilization is key for accurate research.
    • Standardized approaches, like the defined daily dose, enhance comparability.
    • Continued development in drug utilization research is vital for public health insights.