Related Experiment Video
Updated: Oct 27, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Developmental Status of Five-Year-old Children with Very-Low-Birth-Weight
Reza Sharafi1, Afagh Hassanzadeh Rad1, Narges Akrami1
11.Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Insights
Five-year-old very-low-birth-weight (VLBW) children show higher risks for developmental delays in communication, motor, and problem-solving skills compared to normal-birth-weight peers. Early developmental screening is crucial for timely interventions in VLBW infants.
Area of Science:
- Pediatrics
- Developmental Psychology
- Neonatal Care
Background:
- Improved survival rates for very-low-birth-weight (VLBW) neonates have been reported.
- However, a significant percentage of VLBW infants experience developmental disorders.
- Early detection and intervention are critical for addressing developmental challenges in VLBW children.
Purpose of the Study:
- To assess the developmental status of five-year-old children born with very-low-birth-weight (VLBW).
- To compare the developmental outcomes of VLBW children with those of normal-birth-weight (NBW) children at age five.
Main Methods:
- A historical cohort study involving 106 five-year-old children, divided into VLBW and NBW groups.
- Developmental status was evaluated using the Ages and Stages Questionnaire (ASQ), assessing communication, gross motor, fine motor, problem-solving, and personal/social skills.
- Statistical analysis included descriptive statistics, Mann-Whitney U test, and independent t-test using SPSS version 22.
Main Results:
- Significant differences were observed between VLBW and NBW groups in communication (P=0.002), gross motor (P<0.001), fine motor (P<0.001), and problem-solving (P<0.001) skills.
- No significant difference was found in personal/social developmental status between the two groups (P=0.559).
- VLBW children exhibited a higher risk of developmental delays across multiple domains.
Conclusions:
- VLBW infants face a higher risk of developmental delays compared to normal-birth-weight neonates.
- Developmental screening tests are recommended for early identification of high-risk children.
- Timely diagnostic and therapeutic interventions are essential for improving outcomes in VLBW children.
Objective:
Some previous studies have reported the improved survival of very-low-birth-weight (VLBW) neonates with no disabilities. However, 16% of these neonates have developmental disorders. Considering the lack of research on the developmental status of five-year-old VLBW children and the importance of early detection and treatment, in this study, we aimed to assess the developmental status of five-year-old VLBW children.
Materials & Methods:
This historical cohort study was conducted on five-year-old children. The participants were divided into VLBW and normal-birth-weight (NBW) groups. Data were gathered using the Ages and Stages Questionnaire (ASQ). This questionnaire consisted of five developmental domains, including communication, gross motor, fine motor, problem-solving, and personal/social skills. Data were reported by measuring descriptive statistics, including mean, standard deviation, number, and percentage, and analyzed by Mann-Whitney U test and independent t-test in SPSS version 22.
Results:
A total of 106 five-year-old children, including two groups of VLBW and NBW, participated in this study. The results of Mann-Whitney U test showed a significant difference between the groups regarding the scores of communication (P=0.002), gross motor (P<0.001), fine motor (P<0.001), and problem-solving (P<0.001) skills. However, no significant difference was found between the groups regarding the personal/social developmental status (P=0.559).
Conclusion:
According to the results, a higher risk of developmental delay was observed in VLBW infants as compared to NBW neonates; therefore, it is recommended to perform developmental screening tests for timely detection of high-risk children and early diagnostic and therapeutic interventions.
Related Concept Videos
Socioemotional Development during Infancy
Primary Temperament Types
Introduction to Developmental Psychology
Intellectual Disability
Drug Dosing: Infants and Children
Learning Disabilities
Dyslexia
Dyslexia is a...
Nature and Nurture

