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A Biomedical Knowledge Graph System to Propose Mechanistic Hypotheses for Real-World Environmental Health

Karamarie Fecho1,2, Chris Bizon1, Frederick Miller3

  • 1Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

JMIR Medical Informatics
|July 20, 2021
PubMed
Summary

The Reasoning Over Biomedical Objects linked in Knowledge Oriented Pathways (ROBOKOP) system validated associations between workplace exposures and immune-mediated diseases. ROBOKOP generated mechanistic hypotheses for these links, aiding scientific discovery.

Keywords:
data explorationdiscoverygeneralizabilityimmune-mediated diseaseknowledge graphknowledge representationopen science

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