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Epibulbar Subconjunctival Apocrine Hidrocystoma.

Norman C Charles1,2, Leela V Raju1, Eleanore T Kim1

  • 1Department of Ophthalmology.

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|July 20, 2021
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Summary

Apocrine hidrocystomas are rare benign cystic tumors of sweat glands. This report details an exceptional case of an epibulbar subconjunctival apocrine hidrocystoma, offering insights into its presentation and pathology.

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Oncology

Background:

  • Apocrine hidrocystomas are benign cystic tumors originating from apocrine sweat glands.
  • They typically manifest on the head and neck, with ophthalmic cases often near the eyelid margins.

Observation:

  • A 57-year-old woman presented with a unique, mobile epibulbar subconjunctival apocrine hidrocystoma.
  • The patient had no prior history of ocular trauma or surgery.

Findings:

  • Histopathology revealed an empty cyst lined by double-layered cuboidal epithelium.
  • The inner epithelial layer showed apical decapitation secretion, confirmed by PAS staining.
  • Immunohistochemistry demonstrated positivity for cytokeratin-7, smooth muscle actin, D2-40, and CDGFP-15.

Implications:

  • This case expands the known locations of apocrine hidrocystomas within the ocular adnexa.
  • Understanding the histopathological and immunohistochemical features is crucial for accurate diagnosis of these rare orbital tumors.