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Coronary heart disease in the diabetic African: frequency clinical and angiographic features
Insights
Coronary heart disease (CHD) affects 10% of Black African diabetic patients studied. While clinical profiles are similar, diabetics had higher cholesterol, and non-diabetics had higher smoking rates.
Area of Science:
- Cardiology
- Diabetology
- Public Health
Background:
- Coronary heart disease (CHD) is a significant concern in diabetic populations.
- Understanding the specific features of CHD in Black African diabetic patients is crucial for targeted interventions.
Purpose of the Study:
- To determine the frequency of CHD in Black African diabetic patients.
- To compare the clinical and coronarographic features of CHD in diabetic versus non-diabetic patients.
Main Methods:
- Part I: Assessed 50 diabetic patients (40-60 years, <20 years diabetes history) using stress tests and coronary arteriography.
- Part II: Retrospectively analyzed 104 CHD patients (27 diabetic, 77 non-diabetic) comparing clinical and coronarographic data.
Main Results:
- 10% of selected diabetic patients had CHD, with varying degrees of coronary artery involvement.
- Diabetic and non-diabetic CHD patients shared similar clinical profiles (sex, age, angina, MI, mortality).
- Diabetic CHD patients exhibited higher blood cholesterol, while non-diabetics had higher rates of cigarette smoking.
Conclusions:
- CHD is present in a notable percentage of Black African diabetic patients.
- Risk factor profiles differ between diabetic and non-diabetic CHD patients, with implications for prevention strategies.
Abstract:
The frequency and clinical and coronarographic features of coronary heart disease (CHD) in black African diabetic patients were assessed in a two-part study. The aim of part I was to determine the frequency of CHD in 50 diabetic patients selected by the following criteria: male, age between 40 and 60 years, diabetes history less than 20 years, no history of CHD and normal E.K.G. All 50 of these patients underwent a stress test and those who failed or for whom results were inconclusive were submitted to coronary arteriography. Part II was a retrospective study of 104 patients with CHD. Its aim was to compare the clinical and coronarographic features of CHD patients with (27 cases) and without (77 cases) diabetes mellitus. The frequency of CHD in the 50 diabetics selected for this study was 10% (31 negative exercise tests, 19 inconclusive exercise tests, 5 coronary arteriographies with significant narrowing). Of these 5 diabetics with CHD, 3 had single vessel involvement (left descending artery: 2 cases, circumflex artery: 1 case), 1 patient had double vessel involvement (right coronary circumflex artery) and 1 had triple vessel involvement (left descending, circumflex, and right coronary artery). In the retrospective study the clinical profile of the diabetic and non-diabetic CHD patients was the same with respect to sex, age, angina, myocardial infarction, and death rate. As regard the risk factors, blood cholesterol level was higher in diabetics while cigarette smoking was higher in non-diabetics. The frequency of hypertension was the same in both groups.(ABSTRACT TRUNCATED AT 250 WORDS)