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Penile necrosis and calciphylaxis.

José Henrique Gomes Torres1, Sílvia Caroline Neves Ribeiro1, Iure Carvalho de Souza1

  • 1Hospital Santa Marcelina, Brazil.

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|July 21, 2021
PubMed
Summary
This summary is machine-generated.

Penile necrosis, a rare complication of calcific uremic arteriolopathy, affects end-stage renal disease patients. A severe case requiring penectomy highlights survival possibilities despite high mortality rates.

Keywords:
CalciphylaxisEnd-stage-renal-diseasePenectomyPenile necrosis

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Area of Science:

  • Nephrology
  • Vascular Medicine
  • Dermatology

Background:

  • Penile necrosis is a rare but severe condition, often linked to calcific uremic arteriolopathy (calciphylaxis).
  • Calciphylaxis affects 1%-4% of patients with end-stage renal disease (ESRD), carrying a high mortality rate.
  • Penile involvement in calciphylaxis is particularly uncommon and associated with a grave prognosis.

Observation:

  • A severe case of penile calciphylaxis was observed in an end-stage renal disease patient.
  • The condition progressed to necessitate a penectomy.
  • The patient survived the surgical intervention and the acute phase of the penile event.

Findings:

  • This case demonstrates that even severe penile necrosis due to calciphylaxis can be managed surgically.
  • Successful penectomy in this context offers a chance of survival against a typically fatal condition.
  • The patient's survival post-penectomy underscores the importance of aggressive management strategies.

Implications:

  • Aggressive surgical management, including penectomy, may be a viable option for penile necrosis in calciphylaxis.
  • This case expands the understanding of potential treatment outcomes for penile calciphylaxis.
  • Further research into managing calciphylaxis complications in ESRD patients is warranted to improve survival rates.