Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spectroscopic Studies of 6-Membered Lipoic Acid Derivative, 1,2,3-Trithiane-4-pentanoic Acid, and Its Characteristic Stereochemical Profiles.

Molecules (Basel, Switzerland)·2026
Same author

Photocontrol of Non-Adherent Cell Adhesion via Azobenzene-PEG-Lipid/Cyclodextrin Host-Guest Interactions.

International journal of molecular sciences·2026
Same author

Microhand Platform Equipped with Plate-Shaped End-Effectors Enables Precise Probing of Intracellular Structure Contribution to Whole-Cell Mechanical Properties.

Micromachines·2025
Same author

Synthesis and application of phenol-grafted rhamnan sulfate for 3D bioprinting.

Journal of biomaterials science. Polymer edition·2024
Same author

Micromixer driven by bubble-induced acoustic microstreaming for multi-ink 3D bioprinting.

Lab on a chip·2024
Same author

Characterization of Chitosan Hydrogels Obtained through Phenol and Tripolyphosphate Anionic Crosslinking.

Polymers·2024

Related Experiment Video

Updated: Oct 27, 2025

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

16.0K

Bio-assembling and Bioprinting for Engineering Microvessels from the Bottom Up.

Xiaoming Liu1, Tao Yue2,3, Masaru Kojima4

  • 1Key Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, and School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China.

International Journal of Bioprinting
|July 21, 2021
PubMed
Summary

Engineered microvessels are crucial for nutrient delivery in 3D tissues. This review explores bottom-up fabrication methods like bio-assembly and bioprinting for creating functional microvascular networks.

Keywords:
Bio-assemblingBioprintingBottom-upMicrovesselsTissue engineering

More Related Videos

Micropatterning and Assembly of 3D Microvessels
13:05

Micropatterning and Assembly of 3D Microvessels

Published on: September 9, 2016

12.0K
Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies
08:31

Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies

Published on: May 19, 2022

4.1K

Related Experiment Videos

Last Updated: Oct 27, 2025

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

16.0K
Micropatterning and Assembly of 3D Microvessels
13:05

Micropatterning and Assembly of 3D Microvessels

Published on: September 9, 2016

12.0K
Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies
08:31

Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies

Published on: May 19, 2022

4.1K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Vascular Biology

Background:

  • Blood vessels are vital for nutrient transport and homeostasis.
  • Engineered microvessels are needed for nutrient diffusion in 3D tissues.
  • Traditional methods struggle to create functional microvascular networks.

Purpose of the Study:

  • To review bottom-up approaches for microvessel fabrication.
  • To compare bio-assembly and bioprinting methods for microvessel engineering.
  • To discuss future directions in bottom-up microvascular network construction.

Main Methods:

  • Review of existing literature on bottom-up microvessel fabrication.
  • Introduction of bio-assembly techniques using micromanipulation.
  • Discussion of bioprinting strategies with varied solidification mechanisms.

Main Results:

  • Comparison of bio-assembled and bioprinted microvessels.
  • Analysis of features of artificial microvessels from different strategies.
  • Identification of challenges and potential solutions in microvessel engineering.

Conclusions:

  • Bottom-up approaches offer a promising strategy for microvascular network regeneration.
  • Bio-assembly and bioprinting present distinct advantages and disadvantages.
  • Further research is needed to optimize bottom-up fabrication for engineered organs.