Innovate to secure the future: the future of modern medicine

Area of Science:

• Global Health Security
• Infectious Disease Epidemiology
• One Health Approach

Background:

• Antimicrobial resistance (AMR) is a growing global threat, diminishing the effectiveness of treatments for humans and animals.
• Current annual deaths from AMR reach 700,000, with projections indicating a rise to 10 million by 2050 without intervention.
• The complexity and cost of treating infections are increasing due to widespread drug resistance.

Purpose of the Study:

• To highlight the urgent need for intensified research into the drivers and impacts of AMR.
• To emphasize the necessity of translating evidence into sustainable, tailored actions for human, animal, and environmental health.
• To advocate for increased collaboration and transparency in AMR research to strengthen global health security.

Main Methods:

• Review of current global AMR research landscape.
• Analysis of the interconnectedness of AMR across human, animal, and environmental health sectors.
• Exploration of strategies for intensifying research and translating findings into practice.

Main Results:

• Significant research is ongoing globally in areas like new treatments, diagnostics, vaccines, and behavioral interventions.
• There is a critical need for more evidence on AMR drivers and impacts, particularly the links between different health sectors.
• Effective containment requires turning evidence into actionable, sustainable strategies centered on clinicians and patients.

Conclusions:

• Intensified, collaborative, and transparent research is essential to mitigate AMR.
• A One Health approach is vital to address the complex drivers and impacts of AMR.
• Strengthening global health security relies on securing the future of modern medicine through sustained action against AMR.