Related Experiment Video

Updated: Oct 27, 2025

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

7.5K

How do I think about blood donor eligibility criteria for medical conditions?

Mindy Goldman1,2

  • 1Medical Affairs and Innovation, Canadian Blood Services, Ottawa, Ontario, Canada.

Transfusion
|July 21, 2021
PubMed

Insights

Determining blood donor eligibility for medical conditions requires careful consideration of donor and recipient safety. This paper outlines Canada

Area of Science:

  • Transfusion Medicine
  • Hematology
  • Public Health

Background:

  • Blood donor eligibility criteria for medical conditions are often based on limited data and vary significantly.
  • Establishing these criteria impacts donor safety, recipient safety, and blood product quality.

Purpose of the Study:

  • To outline the potential impacts of donor medical conditions on safety and product quality.
  • To describe a multidisciplinary approach to addressing donor eligibility criteria.
  • To provide practical considerations for decision-making regarding donor eligibility.

Main Methods:

  • Review of existing literature and practices.
  • Description of a multidisciplinary expert panel approach.
  • Distillation of years of experience into practical guidelines.

Main Results:

  • Identified potential risks associated with donor medical conditions.
  • Proposed a structured, collaborative approach to criteria development.
  • Highlighted key factors for implementing changes in eligibility criteria.

Conclusions:

  • A systematic, multidisciplinary approach is essential for developing robust blood donor eligibility criteria.
  • Practical considerations and evidence-based data are crucial for ensuring blood supply safety and quality.
  • This framework aims to assist medical and technical staff in making informed decisions on donor eligibility.

Keywords:
blood center operationsdonors

More Related Videos

Routine Screening Method for Microparticles in Platelet Transfusions09:49

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

16.1K
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.7K

Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
958
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
591
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
98
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
12.0K
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
652
Blood Types02:20

Blood Types

Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
19.8K