Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Observational, Multicenter, Parallel-Cohort Study Evaluating the Association of Clinical Manifestations and Patient-Reported Outcomes in Patients with <i>Demodex</i> Blepharitis.

Clinical optometry·2026
Same author

Correcting Astigmatism Using Toric Intraocular Lenses During Cataract Surgery.

American journal of ophthalmology·2026
Same author

International consensuses and guidelines on multifocal intraocular lenses (IOLs) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO).

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2025
Same author

Reply : Ray-tracing-guided myopic LASIK: real-world clinical outcomes.

Journal of cataract and refractive surgery·2025
Same author

Meta-analysis of defocus curves of monofocal, enhanced monofocal and extended depth of focus IOLs.

BMJ open ophthalmology·2025
Same author

A review of angle kappa and multifocal intraocular lenses and their effect on visual outcomes.

Acta ophthalmologica·2025

Related Experiment Video

Updated: Oct 27, 2025

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

220

New methodology for measuring intraocular lens performance using acuity reserve.

Ruth Lapid-Gortzak1, Chandra Bala, Jim Schwiegerling

  • 1From the Amsterdam UMC University of Amsterdam, Retina Total Eye Care, Driebergen, the Netherlands (Lapid-Gortzak); Macquarie University, Sydney, NSW, Australia (Bala); College of Optical Sciences, University of Arizona, Tucson, Arizona (Schwiegerling); Alcon Vison LLC, Fort Worth, Texas (Suryakumar).

Journal of Cataract and Refractive Surgery
|July 22, 2021
PubMed
Summary

A new acuity reserve analysis using area under the curve (AUC) method validates intraocular lens (IOL) assessment. This technique showed the PanOptix Trifocal IOL offers superior intermediate vision compared to the AT LISA Trifocal IOL.

More Related Videos

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.9K
Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

7.7K

Related Experiment Videos

Last Updated: Oct 27, 2025

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

220
Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.9K
Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

7.7K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optometry

Background:

  • Intraocular lens (IOL) assessment is crucial for visual outcomes after cataract surgery.
  • Traditional methods like defocus curves provide valuable data but may not capture the full spectrum of visual performance.
  • Acuity reserve analysis offers a novel approach to quantify visual performance across various distances.

Purpose of the Study:

  • To validate a new methodology for intraocular lens (IOL) assessment using acuity reserve analysis via area under the curve (AUC).
  • To evaluate intermediate vision capabilities of different trifocal IOLs using this novel method.

Main Methods:

  • Post hoc analysis of defocus curve data from two clinical trials involving AcrySof IQ PanOptix Trifocal IOL and AT LISA Trifocal IOL.
  • Acuity reserve was calculated using AUC, comparing visual demand (logMAR) at different distances.
  • Study 1 validated the AUC model, while Study 2 compared acuity reserve between the two IOLs.

Main Results:

  • Study 1 demonstrated good visual acuity (>20/25) across all defocus levels, with AUC indicating over 2 lines of reserve at -2.50 diopters.
  • Study 2 revealed significantly improved acuity reserve with the PanOptix IOL compared to the AT LISA IOL at 20-40 and 120-180 days postoperatively (P < .001).

Conclusions:

  • Acuity reserve analysis using AUC is a novel methodology for comparative IOL assessment, offering more detail than standard defocus curves.
  • The PanOptix Trifocal IOL demonstrated superior visual acuity at near to intermediate distances compared to the AT LISA Trifocal IOL when assessed with acuity reserve analysis.