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Biosynthesis of napyradiomycins
K Shiomi1, H Iinuma, H Naganawa
1Institute of Microbial Chemistry, Tokyo, Japan.
The Journal of Antibiotics
|December 1, 1987
Abstract:
Biosynthetic studies on napyradiomycins were carried out based on the incorporation of [2-13C]acetate and [1,2-13C]acetate. The alignment of acetate units suggested that the B and C rings of napyradiomycins are derived from a pentaketide, while ring A and the side chain may be synthesized from mevalonate.