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Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
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A patient with concurrent multiple sclerosis and moyamoya disease
Prateeka Koul1, Arpan Patel1, Frasat Chaudhry2
1Department of Neurology, North Shore University Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY.
Multiple Sclerosis and Related Disorders
|July 22, 2021
Summary
This case report details a patient diagnosed with both Moyamoya disease (MMD) and Multiple Sclerosis (MS). The coexistence of these distinct neurological conditions highlights potential shared underlying factors.
Area of Science:
- Neurology
- Immunology
- Vascular Medicine
Background:
- Moyamoya disease (MMD) is a rare progressive cerebrovascular disorder.
- Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
- Literature often discusses MMD misdiagnosis as MS-mimics, not their coexistence.
Observation:
- A 57-year-old woman presented with gait issues and foot paresthesias.
- Cerebral and spinal MRI showed lesions indicative of MS.
- Vessel imaging revealed multivessel stenosis characteristic of MMD.
Findings:
- Diagnostic lumbar puncture confirmed oligoclonal bands, supporting an MS diagnosis.
- The patient received concurrent diagnoses of both Multiple Sclerosis and Moyamoya disease.
- This case presents a rare instance of simultaneous MMD and MS.
Implications:
- The co-occurrence of MS and MMD may suggest a shared underlying susceptibility to autoimmunity.
- Further research is warranted to explore potential pathogenetic links between MMD and autoimmune diseases.
- This case broadens the understanding of neurological disease presentations and co-morbidities.
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