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Novel Ag/cellulose-doped CeO2 quantum dots for efficient dye degradation and bactericidal activity with molecular
1Solar Cell Application Research Lab, Department of Physics, Government College University Lahore, Lahore 54000, Punjab, Pakistan.
Carbohydrate Polymers
|July 23, 2021
Summary
Novel Ag/cellulose nanocrystal-doped cerium oxide quantum dots efficiently degrade methylene blue and ciprofloxacin in wastewater. These materials also exhibit significant antimicrobial activity against Gram-negative bacteria.
Area of Science:
- Materials Science
- Nanotechnology
- Environmental Chemistry
Background:
- Wastewater contamination by dyes and pharmaceuticals poses environmental risks.
- Developing efficient catalysts for pollutant degradation is crucial.
- Antimicrobial resistance necessitates novel antibacterial agents.
Purpose of the Study:
- Synthesize novel Ag/cellulose nanocrystal (CNC)-doped cerium oxide (CeO2) quantum dots (QDs).
- Evaluate their catalytic efficiency in degrading methylene blue and ciprofloxacin (MBCF).
- Assess their antimicrobial activity against Gram-negative and Gram-positive bacteria.
Main Methods:
- One-pot co-precipitation synthesis of Ag/CNC-doped CeO2 QDs.
- Catalytic degradation experiments in acidic medium.
- Antimicrobial activity testing using inhibition zone measurements.
- In silico molecular docking against bacterial enzyme targets (DHFR, DHPS, DNA gyrase).
Main Results:
- Achieved 99.3% degradation of MBCF with 4% Ag dopant concentration.
- Demonstrated significant antimicrobial activity against Gram-negative bacteria compared to Gram-positive.
- Molecular docking provided insights into the mechanism of bactericidal action.
Conclusions:
- Ag/CNC-doped CeO2 QDs are highly efficient catalysts for wastewater remediation.
- These nanomaterials exhibit promising broad-spectrum antimicrobial properties.
- In silico studies support the potential of these materials as antibacterial agents.
