Anatomic Approach to Transseptal Puncture for Structural Heart Interventions
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Updated: Oct 27, 2025

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Trevor Simard1, Abdallah El Sabbagh2, Colleen Lane1
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Abstract:
The use of transseptal puncture continues to rise given the increase in left atrial cardiac interventions. The authors review an anatomic approach to transseptal puncture incorporating multimodality imaging both pre- and intraprocedurally with stepwise escalation algorithms to ensure safe and efficacious large-bore transseptal puncture.
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