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Published on: November 7, 2020
Care and Precision Medicine Research in the Time of COVID-19
Juliana M Ison1, Elizabeth W Karlson2,3,4, Jonathan D Jackson1,3,4
1CARE Research Center, Massachusetts General Hospital, Boston, MA.
Purpose:
Enhancing the bidirectional benefit of precision medicine research infrastructure may advance equity in research participation for diverse groups. This study explores the use of research infrastructure to provide human-centered COVID-19 resources to participants as a part of their research participation.
Design:
The All of Us New England (AoUNE) consortium research team developed standardized check-in telephone calls to ask participants about their well-being and share COVID-19 resources.
Participants:
A total of 20,559 participants in the AoUNE consortium received a COVID-19 check-in call.
Methods:
Research assistants called participants during March-April 2020, distributed COVID-19 resources to interested participants, and subsequently rated call tone.
Results:
Of the total cohort participants called, 8,512 (41%) spoke with a research team member. The majority of calls were rated as positive or neutral; only 3% rated as negative. African American and Black as well as Hispanic populations requested COVID-19 resources at higher rates than other groups.
Conclusions:
Calls made to AoUNE participants were received positively by diverse groups. These findings may have implications for participant-centered engagement strategies in precision medicine research.
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