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Persistent fifth aortic arch: a single-center experience, case series.

Yuanyuan Liu1, Hui Zhang2, Jun Ren1

  • 1Division of Cardiology, the Affiliated Children's Hospital of Capital Institute of Pediatrics, Beijing, China.

Translational Pediatrics
|July 23, 2021
PubMed
Summary
This summary is machine-generated.

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Persistent fifth aortic arch (PFAA) is a rare congenital heart defect. Echocardiography is useful for diagnosis, with computed tomography angiography (CTA) confirming uncertain cases.

Area of Science:

  • Cardiovascular Medicine
  • Pediatric Cardiology
  • Medical Imaging

Background:

  • Persistent fifth aortic arch (PFAA) is an exceptionally rare congenital cardiovascular malformation with limited existing literature.
  • Understanding and diagnosing PFAA is challenging due to its rarity.

Purpose of the Study:

  • To enhance the understanding and diagnosis of PFAA using echocardiography and computed tomography angiography (CTA).
  • To evaluate the diagnostic utility of echocardiography for PFAA.

Main Methods:

  • Retrospective review of five PFAA cases diagnosed between October 2016 and September 2019.
  • Analysis of echocardiography and CTA findings, alongside patient medical history.

Main Results:

Keywords:
Persistent fifth aortic arch (PFAA)case seriescomputed tomography angiography (CTA)echocardiographysurgery

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  • Five pediatric patients (3-48 months) with PFAA were identified, presenting with varied clinical symptoms.
  • Echocardiography provided a direct diagnosis in three cases, while two required supplemental CTA confirmation after initial misdiagnosis.
  • Three patients required surgery, with two undergoing the procedure; two patients needed follow-up assessments with positive outcomes.
  • Conclusions:

    • Atypical clinical manifestations of PFAA necessitate reliance on imaging modalities for diagnosis.
    • Echocardiography is a key diagnostic tool, with CTA essential for confirming uncertain findings.
    • Accurate diagnosis of PFAA and associated anomalies is critical for timely and effective treatment, despite ongoing debate regarding nomenclature and embryological origin.