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Updated: Oct 27, 2025

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
Evolution of anodised titanium for implant applications.
1Department of Chemical Engineering Technology, Faculty of Engineering Technology, Universiti Tun Hussein Onn Malaysia (UTHM), Pagoh Higher Education Hub, 84600 Muar, Johor, Malaysia.
Anodised titanium coatings enhance bone integration for implants. This review details their evolution, surface treatments, and future challenges for clinical translation.
Area of Science:
- Biomaterials Science
- Orthopedic Engineering
- Surface Chemistry
Background:
- Anodised titanium is a well-established implant coating due to its bioactive surface promoting bone integration.
- Growing research necessitates a comprehensive review of anodised titanium's development and applications.
Purpose of the Study:
- To review the evolution of anodised titanium as an implant coating.
- To discuss engineering processes, influencing factors, bioactivity, and surface treatments.
- To explore future trends and clinical translation challenges.
Main Methods:
- Literature review of anodised titanium for implant coatings.
- Analysis of formation mechanisms, bioactivity, and surface treatments.
- Discussion of future functional trends and clinical challenges.
Main Results:
- Detailed review of anodised titanium's structure-property relationships.
- Identification of factors influencing anodisation and bioactivity.
- Exploration of advanced surface treatments and biocomposite designs.
Conclusions:
- Anodised titanium shows significant potential for bone implants, with ongoing research focusing on enhancing its performance.
- Key challenges for clinical translation include improving mechanical stability, developing advanced testing methods, and ensuring cost-effectiveness and safety.
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