Related Experiment Video
Updated: Oct 27, 2025

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as A Novel Detection and Quantification Method
Published on: October 7, 2025
miRAnno-network-based functional microRNA annotation
Tomas Tokar1, Chiara Pastrello1, Mark Abovsky1
1Osteoarthritis Research Program Division of Orthopedic Surgery Schroeder Arthritis Institute, and Data Science Discovery Centre for Chronic Diseases Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Motivation:
Functional annotation is a common part of microRNA (miRNA)-related research, typically carried as pathway enrichment analysis of the selected miRNA targets. Here, we propose miRAnno, a fast and easy-to-use web application for miRNA annotation.
Results:
miRAnno uses comprehensive molecular interaction network and random walks with restart to measure the association between miRNAs and individual pathways. Independent validation shows that miRAnno achieves higher signal-to-noise ratio compared to the standard enrichment analysis.
Availability And Implementation:
miRAnno is freely available at https://ophid.utoronto.ca/miRAnno/.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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