Related Experiment Video
Updated: Oct 27, 2025
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
Retinal electrophysiological changes related to early versus late silicone oil removal
Haitham Y Al-Nashar1, Sherif A Dabbour2, Mohammed A Alnaimy2
1Faculty of Medicine, Zagazig University, Zagazig, Egypt. haithamnashar@hotmail.com.
Purpose:
To compare between the effect of early (3 months) and late (6 months) silicone removal on the electroretinogram records.
Methods:
Thirty-four eyes with complex primary rhegmatogenous macula off retinal detachment undergone vitrectomy. Silicone oil was removed after 3 months in group I and after 6 months in group II. Scotopic and photopic ERGs, pattern electroretinogram (PERG) and multifocal ERG (mfERG) and best-corrected visual acuity (BCVA) were recorded for all eyes RESULTS: Preoperative mean best corrected visual acuity (BCVA) measured was 0.93 ± 0.05 in group I and 0.9 ± 0.08 in group II. One month after silicone removal, mean BCVA was 0.20 ± 0.04 and 0.18 ± 0.02 in groups I and II respectively. Before silicone oil removal the electroretinographic a- and b-waves were greatly reduced in both groups with no significant difference between them. One month after removal of silicone oil, the electroretinographic a- and b-waves increased in both groups with no significant difference between the two groups (p = 0.46 and 0.23 respectively).
Conclusion:
The amplitudes of the ERGs increase after removal of silicone oil tamponade with no difference between early (3 months) and late (6 months) removal.
