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FRAMES protocol versus simple advice for medication-overuse headache: a prospective, randomized, controlled clinical
Anna Letícia Moraes Alves1,2, Izadora Karina Silva2, Pedro Henrique Paula Lemos2
1Scientific Initiation Fellowships Institutional Program (CNPq), Recife, Brazil.
Acta Neurologica Belgica
|July 23, 2021
Summary
Both structured (FRAMES) and unstructured counseling effectively reduced medication overuse and headache frequency in patients with Medication-overuse Headache (MOH). However, only the FRAMES approach significantly improved Headache Impact Test scores.
Area of Science:
- Neurology
- Clinical Psychology
Background:
- Medication-overuse Headache (MOH) management requires patients to reduce frequent pain medication use.
- Counseling is a key strategy for behavioral change in MOH treatment.
Purpose of the Study:
- To compare the efficacy of structured (FRAMES) versus unstructured counseling for treating MOH.
- To assess the impact of counseling on medication overuse, headache frequency, and quality of life.
Main Methods:
- A randomized, blind, controlled clinical trial involving 70 patients with MOH.
- Patients received either FRAMES or unstructured counseling, with assessments at baseline, 4, and 8 weeks.
- Data collected via interviews, headache diaries, HIT-6, and HADS.
Main Results:
- Both groups showed significant reductions in headache frequency and acute medication use compared to baseline.
- No significant differences were observed between the groups for primary or secondary outcomes.
- The FRAMES group demonstrated a significant reduction in HIT-6 scores, unlike the control group.
Conclusions:
- Both counseling approaches are effective in reducing pain medication overuse and headache frequency in MOH patients.
- Structured FRAMES counseling may offer additional benefits in improving the impact of headaches on quality of life.
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