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Published on: September 7, 2013
Cutaneous Events Associated with Immunotherapy of Melanoma: A Review
Lorenza Burzi1, Aurora Maria Alessandrini2,3, Pietro Quaglino1
1Department of Medical Sciences, Dermatology Clinic, University of Turin, 10126 Turin, Italy.
Immunotherapy with checkpoint inhibitors significantly improves the outcome for stage III and IV melanoma. Cutaneous adverse events during treatment are often reported. We herein aim to review the principal pigmentation changes induced by immune check-point inhibitors: the appearance of vitiligo, the Sutton phenomenon, melanosis and hair and nail toxicities.
Immunotherapy with checkpoint inhibitors significantly improves the outcome for stage III and IV melanoma. Cutaneous adverse events during treatment are often reported. We herein aim to review the principal pigmentation changes induced by immune check-point inhibitors: the appearance of vitiligo, the Sutton phenomenon, melanosis and hair and nail toxicities.
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