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[Cyberlindnera fabianii: first clinical isolate in Chile]
Eduardo Álvarez Duarte1, Nicolás Cepeda2
1Unidad Micología, Programa Microbiología y Micología, ICBM, Universidad de Chile, Santiago de Chile, Chile.
Revista Iberoamericana De Micologia
|July 24, 2021
Summary
This study reports the first isolation of Cyberlindnera fabianii in Chile. Sequencing the ITS region proved essential for accurate identification, highlighting limitations of conventional methods for this yeast.
Area of Science:
- Medical Mycology
- Microbial Diagnostics
Background:
- Cyberlindnera fabianii is an emerging cause of septicemia.
- Conventional identification methods often misidentify or fail to identify C. fabianii, leading to underdiagnosis.
Observation:
- The first isolation of C. fabianii in Chile is reported.
- Identification was achieved using internal transcribed spacer (ITS) region sequencing.
Findings:
- ITS sequencing confirmed the yeast as C. fabianii, demonstrating its superiority over standard diagnostic tests.
- Phylogenetic analysis revealed the isolated strain's relationship to other yeast species.
Implications:
- Accurate identification of C. fabianii is crucial for appropriate patient management.
- Sequencing techniques are indispensable for identifying challenging or reliably unidentifiable microorganisms.
Keywords:
Antifungal agentsAntifúngicosAnálisis filogenéticoCyberlindnera fabianiiLevadurasPhylogenetic analysisYeastsMore Related Videos
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