Correlation between chronological age and skeletal maturity in different malocclusions: A retrospective study
Related Experiment Video
Updated: Oct 27, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Tabassum Qureshi1, Ritu Duggal1, Prabhat Kumar Chaudhari1
1All India Institute of Medical Sciences, Division of Orthodontics and Dentofacial Deformities, Centre for Dental Education and Research, 110029 New Delhi, India.
Introduction:
The timing of initiation and duration of the pubertal peak is important in dentofacial orthopaedics as the mandible expresses maximum growth during the pubertal peak. The aim of the study was to compare the mean chronological age with skeletal age in three skeletal jaw relations.
Materials And Methods:
The sample consisted of 787 cephalograms divided into class I, class II, and class III skeletal relationship, in which cervical vertebrae stages were assessed. Dunn test was used to compare different types of malocclusion. Pubertal peak duration was assessed by comparing the respective 95% CI.
Results:
There was no statistically significant difference in the mean chronological age in all three malocclusion groups at CS2, CS3, CS4 and CS5. There was no significant difference in the mean age of boys and girls at each CVM stage, but class III boys have significantly delayed maturity during the pubertal spurt at CS4 (14.6 years±0.98) compared with girls (13.3 years±1.48) with P=0.02. The pubertal peak duration was 1.27 years (CI: 0.77-1.76) in the class I children, 0.96 (CI: 0.58-1.34) in the class II children and 1.15 years (CI: 0.26-2.0) in the class III children. In the class III children, the duration of the pubertal peak was higher for boys, 1.74 years (CI: 0.66-2.82) compared with girls, 0.8 years (CI: 0.42-2.82).
Conclusions:
There was positive correlation between chronological age and CVM stages in each skeletal jaw relation. Average time of attaining of a pubertal spurt is similar in class I, class II and class III children. Class III girls reach puberty slightly earlier than boys and puberty ends lately in class III boys. Class II boys have the shortest duration of the pubertal peak and class III boys have the longest duration of the pubertal peak.
Related Concept Videos
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
Introduction to the Skeletal System
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

