Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1000
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1000
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

771
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
771
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

899
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
899

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Divergence between facial expressions and self-reported emotions: Sex differences in responses to video-based emotional stimuli.

PloS oneĀ·2026
Same author

How the Electrochemical Double Layer Manipulates Molecule-Metal Interactions.

ACS nanoĀ·2026
Same author

Beyond Geometric Effects: Particle Size-Dependent Electronic Promotion in Ru Catalysts for Ammonia Synthesis.

Journal of the American Chemical SocietyĀ·2026
Same author

Paeonia suffruticosa root bark extract alleviates gut-brain axis dysfunction in DSS-induced colitis via suppression of intestinal necroptosis and glial activation.

InflammopharmacologyĀ·2026
Same author

Understanding attenuated positive facial expression in depressed women: central role of dorsal raphe network alterations and associated serotonin transporter methylation.

Scientific reportsĀ·2026
Same author

SU-Eohyeol Pharmacopuncture Ameliorates Parkinson's Disease-Associated Pain via the CB1 and PPARĪ³ Pathways in an MPTP-Induced Mouse Model.

Pain research & managementĀ·2026

Related Experiment Video

Updated: Oct 27, 2025

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

19.0K

Wide-field optical coherence tomography deviation map for early glaucoma detection.

Hyungjun Kim1,2, Hae Min Park1,3, Hyo Chan Jeong1,3

  • 1Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of Korea.

The British Journal of Ophthalmology
|July 24, 2021
PubMed
Summary

A new wide-field optical coherence tomography (OCT) deviation map effectively detects early glaucoma (EG). This advanced wide-field OCT map shows superior diagnostic ability compared to existing methods for identifying structural damage in glaucoma patients.

Keywords:
diagnostic tests/investigationglaucomaimaging

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.6K

Related Experiment Videos

Last Updated: Oct 27, 2025

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

19.0K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.6K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Early glaucoma (EG) detection is crucial for preventing vision loss.
  • Current diagnostic methods using peripapillary and macular deviation maps have limitations.
  • Wide-field imaging offers potential for more comprehensive assessment.

Purpose of the Study:

  • To establish a wide-field optical coherence tomography (OCT) deviation map using swept-source OCT (SS-OCT).
  • To compare the diagnostic performance of the wide-field OCT deviation map against conventional maps for early glaucoma detection.

Main Methods:

  • A retrospective observational study included 400 eyes (200 healthy, 200 with EG).
  • Wide-field SS-OCT scans were acquired and processed into a uniform template.
  • A normative wide-field database was used to generate wide-field deviation maps.
  • Diagnostic ability was assessed using the area under the receiver operating characteristic curve (AUC).

Main Results:

  • The wide-field OCT deviation map demonstrated the highest diagnostic ability for EG (AUC=0.980).
  • Its performance was significantly superior to conventional peripapillary and macular deviation maps (p<0.05).
  • The map effectively visualized early structural glaucomatous damage over a wider area.

Conclusions:

  • The wide-field SS-OCT deviation map shows excellent performance in distinguishing early glaucoma from healthy eyes.
  • Its ability to visualize wider areas of damage makes it a valuable tool for clinical diagnosis of EG.